USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q15019 USC-OGP 2-DE database:  Q15019 Q15019 General information about the entry View entry in simple text format Entry name SEPT2_HUMAN Primary accession number Q15019 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Septin-2; AltName: Full=Neural cell expressed developmentally down-regulated protein 5; Short=NEDD-5;. Gene name Name=SEPT2 Synonyms=DIFF6, KIAA0158, NEDD5 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0939: pI=5.97; Mw=42599 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1186: pI=6.36; Mw=43048 Cross-references UniProtKB/Swiss-Prot Q15019; SEPT2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SEPT2_HUMAN Primary accession number Q15019 Secondary accession number(s) B4DGE8 Q14132 Q53QU3 Q8IUK9 Q96CB0 Sequence was last modified on  November 1, 1997 (version 1) Annotations were last modified on  March 15, 2017 (version 186) Name and origin of the protein Description RecName: Full=Septin-2; AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 5; Short=NEDD-5; Gene name Name=SEPT2 Synonyms=DIFF6, KIAA0158, NEDD5 Encoded on Name=SEPT2; Synonyms=DIFF6, KIAA0158, NEDD5 Keywords 3D-structure; Acetylation; Alternative splicing; Cell cycle; Cell division; Cell membrane; Cell projection; Centromere; Chromosome; Complete proteome; Cytoplasm; Cytoskeleton; Differentiation; Direct protein sequencing; GTP-binding; Kinetochore; Membrane; Mitosis; Nucleotide-binding; Phosphoprotein; Reference proteome; Spermatogenesis. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL D63878; BAA09928.2; ALT_INIT; mRNA EMBL D28540; BAA05893.1; -; mRNA EMBL AF038404; AAB92377.1; -; mRNA EMBL AK294563; BAG57759.1; -; mRNA EMBL AC005104; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC104841; AAY14718.1; ALT_SEQ; Genomic_DNA EMBL BC014455; AAH14455.1; -; mRNA EMBL BC033559; AAH33559.1; -; mRNA CCDS CCDS2548.1; -. [Q15019-1]; . CCDS CCDS63195.1; -. [Q15019-3]; . CCDS CCDS74682.1; -. [Q15019-2]; . RefSeq NP_001008491.1; NM_001008491.2. [Q15019-1]; . RefSeq NP_001008492.1; NM_001008492.2. [Q15019-1]; . RefSeq NP_001269901.1; NM_001282972.1. [Q15019-2]; . RefSeq NP_001269902.1; NM_001282973.1. [Q15019-3]; . RefSeq NP_001307958.1; NM_001321029.1; . RefSeq NP_001307959.1; NM_001321030.1. [Q15019-1]; . RefSeq NP_001307960.1; NM_001321031.1. [Q15019-1]; . RefSeq NP_001307961.1; NM_001321032.1. [Q15019-1]; . RefSeq NP_001307962.1; NM_001321033.1. [Q15019-1]; . RefSeq NP_001307963.1; NM_001321034.1. [Q15019-1]; . RefSeq NP_001307964.1; NM_001321035.1. [Q15019-1]; . RefSeq NP_004395.1; NM_004404.4. [Q15019-1]; . RefSeq NP_006146.1; NM_006155.2. [Q15019-1]; . RefSeq XP_016859694.1; XM_017004205.1. [Q15019-1]; . RefSeq XP_016859695.1; XM_017004206.1. [Q15019-1]; . UniGene Hs.721234; -; . PDB 2QA5; X-ray; 3.40 A; A/B=1-315 PDB 2QAG; X-ray; 4.00 A; A=1-361 PDB 2QNR; X-ray; 2.60 A; A/B=22-320 PDBsum 2QA5; -; . PDBsum 2QAG; -; . PDBsum 2QNR; -; . ProteinModelPortal Q15019; -; . SMR Q15019; -; . BioGrid 110812; 86; . DIP DIP-38220N; -; . IntAct Q15019; 27; . MINT MINT-1433588; -; . STRING 9606.ENSP00000353157; -; . iPTMnet Q15019; -; . PhosphoSitePlus Q15019; -; . SwissPalm Q15019; -; . DMDM 2500769; -; . OGP Q15019; -; . EPD Q15019; -; . MaxQB Q15019; -; . PaxDb Q15019; -; . PeptideAtlas Q15019; -; . PRIDE Q15019; -; . TopDownProteomics Q15019-1; -. [Q15019-1]; . DNASU 4735; -; . Ensembl ENST00000360051; ENSP00000353157; ENSG00000168385. [Q15019-1]; . Ensembl ENST00000391971; ENSP00000375832; ENSG00000168385. [Q15019-1]; . Ensembl ENST00000391973; ENSP00000375834; ENSG00000168385. [Q15019-1]; . Ensembl ENST00000401990; ENSP00000385109; ENSG00000168385. [Q15019-3]; . Ensembl ENST00000402092; ENSP00000385172; ENSG00000168385. [Q15019-1]; . Ensembl ENST00000616972; ENSP00000479861; ENSG00000168385. [Q15019-2]; . GeneID 4735; -; . KEGG hsa:4735; -; . UCSC uc002wbc.5; human. [Q15019-1]; . CTD 4735; -; . DisGeNET 4735; -; . GeneCards SEPT2; -; . HGNC HGNC:7729; SEPT2; . HPA CAB017190; -; . HPA HPA018481; -; . MIM 601506; gene; . neXtProt NX_Q15019; -; . OpenTargets ENSG00000168385; -; . PharmGKB PA31535; -; . eggNOG KOG2655; Eukaryota; . eggNOG COG5019; LUCA; . GeneTree ENSGT00870000136374; -; . HOGENOM HOG000233586; -; . HOVERGEN HBG065093; -; . InParanoid Q15019; -; . KO K16942; -; . OMA QFMKAIH; -; . OrthoDB EOG091G07TS; -; . PhylomeDB Q15019; -; . TreeFam TF101079; -; . Reactome R-HSA-5620912; Anchoring of the basal body to the plasma membrane; . SIGNOR Q15019; -; . ChiTaRS SEPT2; human; . EvolutionaryTrace Q15019; -; . GeneWiki SEPT2; -; . GenomeRNAi 4735; -; . PRO PR:Q15019; -; . Proteomes UP000005640; Chromosome 2; . Bgee ENSG00000168385; -; . CleanEx HS_SEPT2; -; . ExpressionAtlas Q15019; baseline and differential; . Genevisible Q15019; HS; . GO GO:0015629; C:actin cytoskeleton; IDA:HPA; . GO GO:0005930; C:axoneme; IDA:GO_Central; . GO GO:0060170; C:ciliary membrane; ISS:UniProtKB; . GO GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell; . GO GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0000145; C:exocyst; IEA:Ensembl; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0030496; C:midbody; IEA:UniProtKB-SubCell; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0097730; C:non-motile cilium; IDA:GO_Central; . GO GO:0005730; C:nucleolus; IDA:HPA; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl; . GO GO:0032391; C:photoreceptor connecting cilium; IDA:GO_Central; . GO GO:0031105; C:septin complex; IDA:UniProtKB; . GO GO:0097227; C:sperm annulus; IDA:UniProtKB; . GO GO:0005819; C:spindle; IEA:UniProtKB-SubCell; . GO GO:0045202; C:synapse; IEA:Ensembl; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0030234; F:enzyme regulator activity; IEA:Ensembl; . GO GO:0005525; F:GTP binding; IEA:UniProtKB-KW; . GO GO:0051301; P:cell division; IEA:UniProtKB-KW; . GO GO:0060271; P:cilium assembly; ISS:UniProtKB; . GO GO:0007067; P:mitotic nuclear division; IEA:UniProtKB-KW; . GO GO:0031175; P:neuron projection development; IEA:Ensembl; . GO GO:0002036; P:regulation of L-glutamate transport; IEA:Ensembl; . GO GO:0032880; P:regulation of protein localization; IEA:Ensembl; . GO GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB; . GO GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW; . CDD cd01850; CDC_Septin; 1; . Gene3D 3.40.50.300; -; 1; . InterPro IPR030379; G_SEPTIN_dom; . InterPro IPR027417; P-loop_NTPase; . InterPro IPR016491; Septin; . InterPro IPR008113; Septin2; . PANTHER PTHR18884; PTHR18884; 1; . Pfam PF00735; Septin; 1; . PIRSF PIRSF006698; Septin; 1; . PRINTS PR01740; SEPTIN2; . SUPFAM SSF52540; SSF52540; 1; . PROSITE PS51719; G_SEPTIN; 1; .

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